Propane (C₃H₈) is a saturated hydrocarbon that has been observed in the murky orange clouds of Titan, the largest moon of Saturn and second largest satellite in the solar system after Ganymede. Propane was first identified in Titan's atmosphere in 1981 by Voyager, but quantification of how much is there in 2003. Propane has also been detected in the atmosphere of Saturn and may also be present on Jupiter. Propane has not been detected to date in the interstellar medium; methane remains the only alkane detected outside the solar system.

Propane is commonly used as a fuel.